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基本信息

杨志禄,研究员,博士生导师

博士学科:材料学

工作单位:材料科学与工程学院、材料先进技术教育部重点实验室

联系方式

通信地址:成都市二环路北一段111号西南交通大学

电子邮箱:zhiluyang1029@126.com; zhiluyang1029@home.swjtu.edu.cn  

 

个人简历

 

杨志禄,工学博士,研究员,博士生导师,西南交通大学“扬华学者”,四川省杰出青年基金获得者,四川省学术和技术带头人后备人选。现任KeAi旗下国际期刊Smart Materials in Medicine(http://www.keaipublishing.com/en/journals/smart-materials-in-medicine/)主编、Engineered Regeneration编委及Medical Gas Research客座编辑。主要研究方向是聚焦心血管动脉粥样硬化病理发病机制、以及用于心血管疾病治疗的纳米靶向药物、药物球囊及具有病灶治愈和血管组织修复功能的血管支架的研究;以第一/通讯作者在Chemistry of Materials,Biomaterials,NPG Asia Materials, ACS Applied Materials and Interfaces,Applied Materials Today等国际期刊上共发表三大检索收录论文40余篇(其中IF>10的论文10篇,IF=8-10的论文7篇)。申请专利20余项(国际发明专利1项,11项获得授权),其中发展的具有完全自主知识产权的“具有病灶治愈和血管组织修复功能的可降解支架涂层”技术已成功实现转让(转让费:1500万)。目前,担任Nature Biomedical Engineering, ACS Nano, Biomaterials, ACS Applied Materials and Interfaces, Chemical Communication等30余种国际期刊的评审人。

 

主要学术任职

 

1、担任Smart materials in medicine 国际期刊共同主编

2、担任Engineered Regeneration 国际期刊编委

3、担任Medical Gas Research 国际期刊客座编辑

4、中国生物材料学会医用金属材料分会委员

5、中国生物材料学会血液净化材料分会委员

6、中国生物材料学会生物材料表界面工程分会委员

 

代表性研究论文

 

16.Qiufen Tu1, Xin Zhao1, Shuai Liu, Xiangyang Li, Qiang Zhang, Han Yu, Kaiqin Xiong, Nan Huang, Zhilu Yang*. Spatiotemporal Dual-Delivery of Therapeutic Gas and Growth Factor for Prevention of Vascular Stent Thrombosis and Restenosis. Applied Materials Today2020. doi.org/10.1016/j.apmt.2019.100546 (IF: 8.013)

15. Hua Qiu1, Pengkai Qi1, Xing Tan, Yu Xiao, Jingxia Liu, Lei Lu, Peng Gao, Ying Yang, Nan Huang*Zhilu Yang*. Biomimetic Engineering Endothelium-like Coating on Cardiovascular Stent through Heparin and Nitric Oxide-Generating Compound Synergic Modification Strategy. Biomaterials. 2019;207:10-22. (IF: 10.273)

14. Qiufen Tu1, Xuehong Shen1, Yaowen Liu, Qiang Zhang, Xin Zhao, Manfred F. Maitz, Tao Liu, Hua Qiu, Jin Wang, Nan Huang*Zhilu Yang*. A facile metal-phenolic-amine strategy for dual-functionalization of blood-contacting devices with antibacterial and anticoagulant properties. Materials Chemistry Frontiers. 2019;3:265-275.

13. Feng Zhang1, Qiang Zhang1, Xiangyang Li, Nan Huang, Xin Zhao*, Zhilu Yang*. Mussel-inspired dopamine-CuII coatings for sustained in situ generation of nitric oxide for prevention of stent thrombosis and restenosis. Biomaterials. 2019;194:117-129. (IF: 10.273)

12. Xiangyang Li, Peng Gao, Jianying Tan, Kaiqin Xiong, Changjiang Pan, Hongkai Wu, Yin Chen, Zhilu Yang*, Nan Huang*. Assembly of Metal-Phenolic/Catecholamine Networks for Synergistically Anti-Inflammatory, Antimicrobial and Anticoagulant Coatings. ACS Applied Materials & Interfaces. 2018;10:40844-40853. (IF: 8.456)

11. Zhilu Yang,* Ying Yang, Kaiqin Xiong, Jin Wang, Haeshin Lee*, Nan Huang*, Metal-Phenolic Surfaces for Generating Therapeutic Nitric Oxide Gas. Chemistry of Materials. 2018;30:5220-5226.(IF: 10.159)

10. Zhilu Yang*, Ying Yang, Li Zhang, Kaiqin Xiong, Xiangyang Li, Feng Zhang, Jin Wanga, Xin Zhao*, Nan Huang*, Mussel-inspired Catalytic Selenocystamine-Dopamine Coatings for Long-Term Generation of Therapeutic Gas on Cardiovascular Stents. Biomaterials. 2018;178:1-10.(IF: 10.273).

9. Xiangyang Li, Hua Qiu, Peng Gao, Ying Yang, Zhilu Yang*, Nan Huang*, Synergetic coordination- and catecholamine chemistry for catalytic generation of nitric oxide on vascular stents. NPG Asia Materials. 2018;10:482–496.(IF: 8.052)

8. Ying Yang, Xiangyang Li, Hua Qiu, Ping Li, Manfred F. Maitz, Tianxue You, Ru Shen, Zhilu Yang*, Wenjie Tian*, and Nan Huang*. Polydopamine modified TiO2 nanotube arrays for long term controlled elution of bivalirudin and improved hemocompatibility. ACS Applied Materials & Interfaces. 2018;10:7649−7660. (IF: 8.456)

7Zhilu Yang*, Ying Yang, Kaiqin Xiong, Xiangyang Li, Pengkai Qi, Qiufen Tu, Fengjuan Jing, Yajun Weng, Jin Wang*, Nan Huang*. Nitric oxide producing coating mimicking endothelium function for multifunctional vascular stents. Biomaterials2015;63:80-92.(IF: 10.273).

6. Zhilu Yang*, Kaiqin Xiong, Pengkai Qi, Ying Yang, Qiufen Tu, Jin Wang*, Nan Huang*. Gallic acid tailoring surface functionalities of plasma-polymerized allylamine-coated 316L SS to selectively direct vascular endothelial and smooth muscle cell fate for enhanced endothelialization. ACS Applied Materials & Interfaces. 2014;6:2647-2656. (IF: 8.456).

5. Ying Yang, Pengkai Qi, Feng Wen, Xiangyang Li, Qin Xia, Manfred F. Maitz, Zhilu Yang*, Ru Shen, Qiufen Tu, Nan Huang*. Mussel-inspired one-step adherent coating rich in amine groups for covalent immobilization of heparin: hemocompatibility, growth behaviors of vascular cells and tissue response. ACS Applied Materials & Interfaces. 2014;6:14608-14620. (IF: 8.456)

4. Zhilu Yang1,*, Ying Yang1, Wei Yan, Qiufen Tu*, Jin Wang*, Nan Huang. Construction of polyfunctional coatings assisted by gallic acid to facilitate co-immobilization of diverse biomolecules. ACS Applied Materials & Interfaces. 2013;5:10495-10501. (IF: 8.456).

3. Zhilu Yang, Qiufen Tu*, Manfred F. Maitz, Shou Zhou, Jin Wang, Nan Huang*. Direct thrombin inhibitor-bivalirudin functionalized plasma polymerized allylamine coating for improved biocompatibility of vascular devices. Biomaterials. 2012;33:7959-7971. (IF: 10.273)

2Zhilu Yang*, Qiufen Tu, Jin Wang*, Nan Huang*. The role of heparin binding surface in the direction of endothelial and smooth muscle cell fate and re-endothelialization. Biomaterials. 2012;33:6615-6625. (IF: 10.273)

1Zhilu Yang, Jin Wang*, Rifang Luo, Manfred F. Maitz, Fengjuan Jing, Hong Sun, Nan Huang. The covalent immobilization of heparin to pulsed-plasma polymeric allylamine films on 316L stainless steel and the resulting effects on hemocompatibility. Biomaterials. 2010;31:2072–2083. (IF: 10.273)

 

 
 

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