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基本信息

杨志禄,副教授

博士学科:材料学

工作单位:材料科学与工程学院、材料先进技术教育部重点实验室

联系方式

通信地址:成都市二环路北一段111号西南交通大学

电子邮箱:zhiluyang1029@126.com; zhiluyang1029@home.swjtu.edu.cn  

办公电话:028-87607691

 

个人简历

杨志禄,工学博士,副教授,硕士生导师,四川省杰出青年基金获得者,西南交通大学“雏鹰学者”及“竢实扬华”奖章获得者。主要研究方向是基于等离子体聚合技术以及儿茶酚灵感化学,结合微图形制造及生物功能分子修饰,构建具有内皮功能仿生的聚合涂层,用于心血管植入、介入器械表面改性方面的应用基础研究;此外,基于儿茶酚灵感化学,结合功能仿生设计,从事有机晶体、多功能水凝胶及纳米粒子的合成及其探索其在抗凝血材料、肿瘤治疗以及心血管植入器械等方面的应用基础研究;综合应用3D打印、儿茶酚灵感化学等多种技术,从事心血管再生医学组织工程方面的研究。2005年获得南昌航空大学高分子材料工程专业工学学士学位,2008年获得西南交通大学材料物理化学专业工学硕士学位,2014年获得西南交通大学材料学专业工学博士学位,2015年破格以副教授引进到西南交通大学材料科学与工程学院材料先进技术教育部重点实验室工作。目前,在Chemistry of Materials,NPG Asia Materials, Biomaterials, ACS Applied Materials and Interfaces,Acta Biomaterialia, Advanced Healthcare Materials等国际期刊上共发表三大检索收录论文40余篇,其中以第一作者身份(通讯作者)在SCI收录杂志上发表30余篇(平均影响因子>5),论文被60余种SCI源期刊总引用1000余次,单篇最高他人引用150余次。申请专利14项(国际发明专利1项), 10项获得授权。目前,担任Biomaterials, ACS Applied Materials and Interfaces, Chemical Communication等20余种国际期刊的评审人。

 

代表性研究论文

15. Hua Qiu1, Pengkai Qi1, Xing Tan, Yu Xiao, Jingxia Liu, Lei Lu, Peng Gao, Ying Yang, Nan Huang*Zhilu Yang*. Biomimetic Engineering Endothelium-like Coating on Cardiovascular Stent through Heparin and Nitric Oxide-Generating Compound Synergic Modification Strategy. Biomaterials. 2019 (IF: 8.806, Accepted)

14. Qiufen Tu1, Xuehong Shen1, Yaowen Liu, Qiang Zhang, Xin Zhao, Manfred F. Maitz, Tao Liu, Hua Qiu, Jin Wang, Nan Huang*Zhilu Yang*. A facile metal-phenolic-amine strategy for dual-functionalization of blood-contacting devices with antibacterial and anticoagulant properties. Materials Chemistry Frontiers. 2019;DOI:10.1039/C8QM00458G.

13. Feng Zhang1, Qiang Zhang1, Xiangyang Li, Nan Huang, Xin Zhao*, Zhilu Yang*. Mussel-inspired dopamine-CuII coatings for sustained in situ generation of nitric oxide for prevention of stent thrombosis and restenosis. Biomaterials. 2019;194:117-129. (IF: 8.806)

12. Xiangyang Li, Peng Gao, Jianying Tan, Kaiqin Xiong, Changjiang Pan, Hongkai Wu, Yin Chen, Zhilu Yang*, Nan Huang*. Assembly of Metal-Phenolic/Catecholamine Networks for Synergistically Anti-Inflammatory, Antimicrobial and Anticoagulant Coatings. ACS Applied Materials & Interfaces. 2018;10:40844-40853. (IF: 8.097)

11. Zhilu Yang,* Ying Yang, Kaiqin Xiong, Jin Wang, Haeshin Lee*, Nan Huang*, Metal-Phenolic Surfaces for Generating Therapeutic Nitric Oxide Gas. Chemistry of Materials. 2018;30:5220-5226.(IF: 9.89)

10. Zhilu Yang*, Ying Yang, Li Zhang, Kaiqin Xiong, Xiangyang Li, Feng Zhang, Jin Wanga, Xin Zhao*, Nan Huang*, Mussel-inspired Catalytic Selenocystamine-Dopamine Coatings for Long-Term Generation of Therapeutic Gas on Cardiovascular Stents. Biomaterials. 2018;178:1-10.(IF: 8.806).

9. Xiangyang Li, Hua Qiu, Peng Gao, Ying Yang, Zhilu Yang*, Nan Huang*, Synergetic coordination- and catecholamine chemistry for catalytic generation of nitric oxide on vascular stents. NPG Asia Materials. 2018;10:482–496.(IF: 7.208)

8. Ying Yang, Xiangyang Li, Hua Qiu, Ping Li, Manfred F. Maitz, Tianxue You, Ru Shen, Zhilu Yang*, Wenjie Tian*, and Nan Huang*. Polydopamine modified TiO2 nanotube arrays for long term controlled elution of bivalirudin and improved hemocompatibility. ACS Applied Materials & Interfaces. 2018;10:7649−7660. (IF: 8.097)

7Zhilu Yang*, Ying Yang, Kaiqin Xiong, Xiangyang Li, Pengkai Qi, Qiufen Tu, Fengjuan Jing, Yajun Weng, Jin Wang*, Nan Huang*. Nitric oxide producing coating mimicking endothelium function for multifunctional vascular stents. Biomaterials2015;63:80-92.(IF: 8.806).

6. Zhilu Yang*, Kaiqin Xiong, Pengkai Qi, Ying Yang, Qiufen Tu, Jin Wang*, Nan Huang*. Gallic acid tailoring surface functionalities of plasma-polymerized allylamine-coated 316L SS to selectively direct vascular endothelial and smooth muscle cell fate for enhanced endothelialization. ACS Applied Materials & Interfaces. 2014;6:2647-2656. (IF: 8.097).

5. Ying Yang, Pengkai Qi, Feng Wen, Xiangyang Li, Qin Xia, Manfred F. Maitz, Zhilu Yang*, Ru Shen, Qiufen Tu, Nan Huang*. A mussel-inspired one-step adherent coating rich in amine groups for covalent immobilization of heparin: hemocompatibility, growth behaviors of vascular cells and tissue response. ACS Applied Materials & Interfaces. 2014;6:14608-14620. (IF: 8.097)

4. Zhilu Yang1,*, Ying Yang1, Wei Yan, Qiufen Tu*, Jin Wang*, Nan Huang. Construction of polyfunctional coatings assisted by gallic acid to facilitate co-immobilization of diverse biomolecules. ACS Applied Materials & Interfaces. 2013;5:10495-10501. (IF: 8.097).

3. Zhilu Yang, Qiufen Tu*, Manfred F. Maitz, Shou Zhou, Jin Wang, Nan Huang*. Direct thrombin inhibitor-bivalirudin functionalized plasma polymerized allylamine coating for improved biocompatibility of vascular devices. Biomaterials. 2012;33:7959-7971. (IF: 8.806)

2Zhilu Yang*, Qiufen Tu, Jin Wang*, Nan Huang*. The role of heparin binding surface in the direction of endothelial and smooth muscle cell fate and re-endothelialization. Biomaterials. 2012;33:6615-6625. (IF: 8.806)

1Zhilu Yang, Jin Wang*, Rifang Luo, Manfred F. Maitz, Fengjuan Jing, Hong Sun, Nan Huang. The covalent immobilization of heparin to pulsed-plasma polymeric allylamine films on 316L stainless steel and the resulting effects on hemocompatibility. Biomaterials. 2010;31:2072–2083. (IF: 8.806)

 

 
 

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